1

Pak R.V. – oncologist, PhD candidate, physician at the Oncogynecology Center of JSC “KazIOR”;
Sadykova T.T. – Candidate of Medical Science, Head of the Consultative and Diagnostic Center at JSC “KazIOR”, Associate Professor of the Department of Oncology at the NCJCK “KazNMU named after S.D. Asfendiyarov”
Ongarbaev B.T. – Deputy Chairman of the Board for Scientific and Clinical Work at JSC “KazIOR”

Implementation of the quality-of-life questionnaire developed by the European Organisation for Research and Treatment of Cancer (The EORTC Quality of Life Questionnaire (QLQ-C30 v. 3.0))

JSC “KazIOR”

The use of a questionnaire translated into Kazakh and adapted for the Kazakhstani audience will allow the identification of impairments in key quality-of-life parameters in patients with cervical cancer who have undergone various types of treatment. This will help in the further development of a rehabilitation algorithm for these patient groups.

2

Pak R.V. – oncologist, PhD candidate, physician at the Oncogynecology Center of JSC “KazIOR”;
Sadykova T.T. – Candidate of Medical Science, Head of the Consultative and Diagnostic Center at JSC “KazIOR”, Associate Professor of the Department of Oncology at the NCJCK “KazNMU named after S.D. Asfendiyarov”
Ongarbaev B.T. – Deputy Chairman of the Board for Scientific and Clinical Work at JSC “KazIOR”

Implementation of the multidimensional self-assessment tool for female sexual function (The Female Sexual Function Index, FSFI)

JSC “KazIOR”

The use of a questionnaire on sexual function, translated into Kazakh and adapted for the Kazakhstani audience, will allow the identification of impairments in key sexual function parameters in patients with cervical cancer who have undergone various types of treatment. This will aid in the further development of a rehabilitation algorithm for these patient groups

3

Pak R.V. – oncologist, PhD candidate, physician at the Oncogynecology Center of JSC “KazIOR”;
Sadykova T.T. – Candidate of Medical Science, Head of the Consultative and Diagnostic Center at JSC “KazIOR”, Associate Professor of the Department of Oncology at the NCJCK “KazNMU named after S.D. Asfendiyarov”
Ongarbaev B.T. – Deputy Chairman of the Board for Scientific and Clinical Work at JSC “KazIOR”

Implementation of developed rehabilitation algorithms for patients treated for cervical cancer

JSC “KazIOR”

Rehabilitation algorithms for patients treated for cervical cancer will help improve quality of life, psychological well-being, and sexual function, as well as significantly reduce long-term urological and gastrointestinal complications associated with the treatment.

4

Ermek Dyusembekov Kavatovich – Chief Researcher of the Scientific and Technical Program, Doctor of Medical Sciences, Head of the Department of Neurosurgery at S.D. Asfendiyarov KazNMU, Head of the Neurosurgery Department at City Clinical Hospital No.7.
Damir Dubchev Ildusovich – Responsible Executor of the Scientific and Technical Program, Candidate of Medical Sciences, Neurosurgeon at KazIOR.

Implementation of the SOP ‘Method of intraoperative fluorescent contrast of primary and secondary brain tumors using 5-aminolevulinic acid (trade name “Gliolan”) at the tumor resection stage.’

JSC “KazIOR”

The use of the SOP allows standardization of the procedure for intraoperative fluorescent contrast of primary and secondary brain tumors using 5-aminolevulinic acid (trade name ‘Gliolan’) at the tumor resection stage. Assigning several center staff members to conduct the scientific study ensures personnel are trained in intraoperative fluorescent contrast techniques in accordance with the study protocol and applicable regulatory requirements

5

Ermek Dyusembekov Kavatovich – Chief Researcher of the Scientific and Technical Program, Doctor of Medical Sciences, Head of the Department of Neurosurgery at S.D. Asfendiyarov KazNMU, Head of the Neurosurgery Department at City Clinical Hospital No.7.
Damir Dubchev Ildusovich – Responsible Executor of the Scientific and Technical Program, Candidate of Medical Sciences, Neurosurgeon at KazIOR

Implementation of the SOP ‘Method of intraoperative fluorescent contrast of primary and secondary brain tumors using 5-aminolevulinic acid (trade name “Gliolan”) at the tumor resection stage.’

State Communal Enterprise on the Right of Economic Management ‘City Clinical Hospital No. 7, Department of Health, Almaty

The use of the SOP allows standardization of the procedure for intraoperative fluorescent contrast of primary and secondary brain tumors using 5-aminolevulinic acid (trade name ‘Gliolan’) at the tumor resection stage. Assigning several center staff members to conduct the scientific study ensures personnel are trained in intraoperative fluorescent contrast techniques in accordance with the study protocol and applicable regulatory requirements

6

D.Z. Baiguisova, G.A. Battalova, Zh.M. Amankulov, A.N. Mukhamedzhanova, M. Saifullakyzy, G.S. Aitbay

Implementation of the methodological guidelines “Indications for Computed Tomography”

JSC “KazIOR”

The developed guidelines are based on modern advances in radiology and the optimization of processes in medical organizations, which contribute to:

-reducing radiation exposure for patients;

-justified performance of necessary examinations;

-efficient use of material and technical resources;

-improving the quality of medical care for the population.”

7

Amankulov Zhandos Muktarovich – Responsible Executor, Researcher of the Scientific and Technical Program, PhD, Head of the Department of Radiology and Nuclear Medicine at KazIOR;
Sadibekova Araylym – Physician of the Department of Radiology and Nuclear Medicine at KazIOR;
Dzhamalov Sulkhi Amanzhanovich – Responsible Executor of the Scientific and Technical Program, Physician of the Department of Radiology and Nuclear Medicine at KazIOR

Implementation of the developed and approved SOP “Conducting Prostate Cancer Therapy with Lu PSMA”

JSC “KazIOR”

The use of the SOP allows standardization of the prostate cancer therapy process with 177Lu PSMA. Assigning several center staff members to conduct the scientific study ensures personnel are trained in 177Lu PSMA prostate cancer therapy in accordance with the study protocol and applicable regulatory requirements.

8

Amankulov Zhandos Muktarovich – Responsible Executor, Researcher of the Scientific and Technical Program, PhD, Head of the Department of Radiology and Nuclear Medicine at KazIOR;
Sadibekova Araylym – Physician of the Department of Radiology and Nuclear Medicine at KazIOR;
Dzhamalov Sulkhi Amanzhanovich – Responsible Executor of the Scientific and Technical Program, Physician of the Department of Radiology and Nuclear Medicine at KazIOR

Implementation of the developed and approved SOP “Conducting PET/CT Imaging with 18F-PSMA”

JSC “KazIOR”

The use of the SOP allows standardization of the PET/CT imaging process with 18F-PSMA. Assigning several center staff members to conduct the scientific study ensures personnel are trained in performing PET/CT imaging with 18F-PSMA in accordance with the study protocol and applicable regulatory requirements

Title of the Patent

Authors

Type of Intellectual Property Document

1

Method for the Diagnosis of Breast Cancer

Zholdybai Zh.Z., Zhakenova Zh.K., Inozemtseva N.I., Ainakulova A.S.

Patent for an invention (EAPO)
№ 036245

2

Surgical treatment of tumors of the skin, soft tissues of the scalp, and cranial vault bones with simultaneous reconstruction of extensive defects using combined skin flaps and application of a fixed pressure dressing

Serikbaev G.A., Tuleuova D.A., Pysanova Zh.U., Kurmanaliev A.K., Ormanov K.M.

Patent for an invention
№33932
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

3

Method for diagnosing breast cancer

Zholdybai Zh.Z., Zhakenova Zh.K., Inozemtseva N.I., Ainakulova A.S.

Patent for an invention
№33709
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

4

Method for early diagnosis of predisposition to breast cancer in the Kazakh ethnic group of women in Kazakhstan

Orazgalieva M.G., Kaidarova D.R., Goncharova T.G., Omarbayeva N.A., Adilbay D.G., Kadyrbayeva R.E., Askandirova A.B.

Patent for an invention
№ 35376
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

5

Method for prognostic stratification of the risk of thyroid cancer recurrence

Sloneva N.V., Orazgalieva M.G., Adilbaev G.B., Adilbay D.G., Kadyrbayeva G.Zh., Shipilova V.V.

Patent for a utility model
№ 6017
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

6

Method for early diagnosis of lung cancer

Kaidarova D.R., Adilbay D.G., Goncharova T.G., Orazgalieva M.G., Kadyrbayeva R.E., Omarbayeva N.A.

Patent for an invention
№ 34716
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

7

Method for molecular-genetic diagnosis and treatment of metastatic colorectal cancer

Smagulova K.K., Ukolova E.A., Kurmankulova A.Zh., Turkpenova I.T., Orazgalieva M.G., Zhunsbekova A.A.

Patent for a utility model
№ 7931
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

8

Method for treating diffuse large B-cell lymphoma

Karakulov R., Gabbasova S.T., Kemelbekov N.A., Dzhazyltaeva A.S., Sagindykov G.A., Nasipov B.A., Karazhanova M.K.

Patent for Invention
№34664
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

9

Method for molecular-genetic diagnosis and treatment of metastatic сolorectal сancer

Smagulova K.K., Ukolova E.A., Kurmankulova A.Zh., Turkpenova I.T., Orazgalieva M.G., Zhunsbekova A.A.

Patent for Invention (EAPO)
№ 044957

10

Method for early diagnosis of breast cancer in women of Kazakhstan based on DNA methylation of mononuclear fraction of peripheral blood plasma

Orazgalieva M.G., Kaidarova D.R., Goncharova T.G., Omarbaeva N.A., Adilbay D.G., Kadyrbaeva R.E., Askandirova A.B.

Patent for Invention (EAPO)
№ 041621

Method for predicting aggressive forms of prostate сancer

Gasanov Z.B., D.R. Kaydarova, A.Zh. Zhylykaĭdarova

Patent for Utility Model
№ 5964
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

12.

Method for the treatment of metastatic brain lesions

Almbek A.T., Kaydarova D.R., Kim V.B., Ibraimova M.A.

Patent for Invention
№ 35861
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

13

Method for early diagnosis of colorectal cancer in the Kazakhstani population based on the use of a multigene testing panel

Afonin G.A., Kaidarova D.R., Baltaev N.A..

14

Method for early diagnosis of colorectal cancer in the screening-age population

Amankulov Zh.M., Kaidarova D.R., Orazgalieva M.G., Goncharova T.G., Dzhumanov A.I., Khozhaev A.A.

Patent for Utility Model
№ 8650
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

15

Method for differential diagnosis of parathyroid gland tumors

Kultaev A.S., Kaidarova D.R., Zakiryarov I.A., Dzhumabekov A.T., Imambetova A.S., Serikbaev G.A., Amankulov Zh.M., Kaibarov M.E., Anarbaev N.B., Mukhtarova Zh.N., Malysheva L.A., Goncharova T.G.

Patent for Invention (EAPO)
№ 050441

№

Title of the Patent

Authors

Type of intellectual property document

1

A set of measures to improve the prevention and screening of breast cancer and colorectal cancer

Zhilkaidarova A.Zh., Kaidarova D.R., Dushimova Z.D., Omarbayeva N.A., Dzhumanov A.I., Goncharova T.G.

АС №7368, 30.12.19
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

2

Technology for early prediction of aggressive forms of prostate cancer

Gasanov Z.B.

АС № 14933, 05.02.21
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

3

Development of rehabilitation algorithms for patients treated for cervical cancer

Pak R.V., Chingisova Zh.K., Kaidarova D.R., Fakhradiev I.R.

АС № 22498, 21.12.21
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

4

Method of using motivational interviewing to increase physical activity in patients with breast cancer

Karibaeva I.A., Madalieva S.Kh., Turdalieva B.S., Kusainova D.N., Bagiyarova F.A.

АС № 28096, 29.07.22
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

5

Algorithm for BRCA1 and BRCA2 mutation testing in Kazakh women with epithelial ovarian cancer

Bolatbekova R.O., Kaidarova D.R., Kukubasov E.K., Goncharova T.G., Orazgalieva M.G.,

АС №39423, 5.10.23
Kazakh National Institute of Intellectual

6

HER2 Breast Cancer Digital Image Dataset (ADEL Dataset). (HER2 breast cancer digital image dataset)

Dunenova Gauhar Abuevna, Glushkova Natalia Egorovna, Sarsembayev Aidos Aidarovich, Satbayeva Elvira Bolatovna, Kalmataeva Zhanna Amantaevna, Kaidarova Dilyara Radikovna

АС № 48772, 01.08.24
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

7

Practical model for providing medical, psychological, and social support at the primary healthcare level for patients with newly diagnosed cancer

Kusainova D.N., Kaidarova D.R., Aimbetova G.E., Bagiyarova F.A., Tursynbekova A.E.

АС № 48481, 18.07.24
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

8

Adapted methodology for studying the burden of oncological diseases in the Republic of Kazakhstan

Kasymbekova Fatima Dautovna, Glushkova Natalia Egorovna, Kaidarova Dilyara Radikovna, Zhetpisbaeva Indira Armanovna, Dyusenov Rasul Serikovich, Dunenova Gauhar Abuevna

АС № 52072, 2.12.24
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

9

Assessment of quality of life and sexual function in women treated for cancer

Pak R.V.

АС № 15169, 15.02.21
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan

10

Advanced training course “Medical and Social Rehabilitation of Oncology Patients”

Uteulova Aliya Askarovna, Bekzhanova Saniya Zharkynbekovna

АС № 61268, 06.08.25
Kazakh National Institute of Intellectual Property, Republic of Kazakhstan